Evaluation of T, B and natural killer lymphocyte in the cervical stroma of HIV-positive and negative patients with cervical intraepithelial neoplasia

Highlights • We compared the expression of T, B lymphocytes, and NK cells in CIN and HIV+/− patients. • The seropositive women had a higher count of cytotoxic T lymphocytes. • Patients with HIV− and CIN 1 had a lower count of B-lymphocytes compared with HIV+ and with CIN 2/3 HIV− patients. • The HIV...

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Veröffentlicht in:Immunology letters 2016-01, Vol.169, p.98-103
Hauptverfasser: Lucena, Adriana A.S, Guimarães, Mírian Viviane M.B, Michelin, Márcia A, Lodi, Cláudia T.C, Lima, Maria Inês M, Murta, Eddie Fernando Candido, Melo, Victor Hugo
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Sprache:eng
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Zusammenfassung:Highlights • We compared the expression of T, B lymphocytes, and NK cells in CIN and HIV+/− patients. • The seropositive women had a higher count of cytotoxic T lymphocytes. • Patients with HIV− and CIN 1 had a lower count of B-lymphocytes compared with HIV+ and with CIN 2/3 HIV− patients. • The HIV infection influenced the cytotoxic lymphocytes. • The degree of CIN influenced the high count of CD20+ lymphocytes with CIN 1.
ISSN:0165-2478
1879-0542
DOI:10.1016/j.imlet.2015.10.016