Advanced Age and Medication Prescription: More Years, Less Medications? A Nationwide Report From the Italian Medicines Agency

Advanced Age and Medication Prescription: More Years, Less Medications? A Nationwide Report From the Italian Medicines Agency

Abstract Background In older adults co-occurrence of multiple diseases often leads to use of multiple medications (polypharmacy). The aim of the present study is to describe how prescription of medications varies across age groups, with specific focus on the oldest old. Methods We performed a cross-...

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Veröffentlicht in:Journal of the American Medical Directors Association 2016-02, Vol.17 (2), p.168-172
Hauptverfasser: Onder, Graziano, MD, PhD, Marengoni, Alessandra, MD, PhD, Russo, Pierluigi, MD, PhD, Degli Esposti, Luca, Econ D, PhD, Fini, Massimo, MD, Monaco, Alessandro, PhD, Bonassi, Stefano, PhD, Palmer, Katie, PhD, Marrocco, Walter, MD, Pozzi, Giuseppe, MD, Sangiorgi, Diego, MStat, Buda, Stefano, MD, Marchionni, Niccolò, MD, Mammarella, Federica, MD, PhD, Bernabei, Roberto, MD, Pani, Luca, MD, Pecorelli, Sergio, MD
Format: Artikel
Sprache:eng
Schlagworte:
Age Distribution
Aged
Aged, 80 and over
Cross-Sectional Studies
Databases, Factual
Drug Prescriptions
end of life
Female
Humans
Internal Medicine
Italy
Male
Medical Education
Polypharmacy
Prescribing
Terminal Care
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Zusammenfassung:Abstract Background In older adults co-occurrence of multiple diseases often leads to use of multiple medications (polypharmacy). The aim of the present study is to describe how prescription of medications varies across age groups, with specific focus on the oldest old. Methods We performed a cross-sectional study using 2013 data from the OsMed Health-DB database (mean number of medicines and defined daily doses prescribed in 15,931,642 individuals). There were 3,378,725 individuals age 65 years or older (21.2% of the study sample). Results The mean number of prescribed medications progressively rose from 1.9 in the age group
ISSN:1525-8610
1538-9375
DOI:10.1016/j.jamda.2015.08.009