Setaria digitata in advancing our knowledge of human lymphatic filariasis
Setaria digitata is a filarial parasite that causes fatal cerebrospinal nematodiasis in goats, sheep and horses, resulting in substantial economic losses in animal husbandry in the tropics. Due to its close resemblance to Wuchereria bancrofti, this nematode is also frequently used as a model organis...
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Veröffentlicht in: | Journal of helminthology 2016-03, Vol.90 (2), p.129-138 |
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creator | Perumal, A.N.I. Gunawardene, Y.I.N.S. Dassanayake, R.S. |
description | Setaria digitata is a filarial parasite that causes fatal cerebrospinal nematodiasis in goats, sheep and horses, resulting in substantial economic losses in animal husbandry in the tropics. Due to its close resemblance to Wuchereria bancrofti, this nematode is also frequently used as a model organism to study human lymphatic filariasis. This review highlights numerous insights into the morphological, histological, biochemical, immunological and genetic aspects of S. digitata that have broadened our understanding towards the control and eradication of filarial diseases. |
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Due to its close resemblance to Wuchereria bancrofti, this nematode is also frequently used as a model organism to study human lymphatic filariasis. This review highlights numerous insights into the morphological, histological, biochemical, immunological and genetic aspects of S. digitata that have broadened our understanding towards the control and eradication of filarial diseases.</description><identifier>ISSN: 0022-149X</identifier><identifier>EISSN: 1475-2697</identifier><identifier>DOI: 10.1017/S0022149X15000309</identifier><identifier>PMID: 25924635</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Animals ; Antigens ; Biology ; Cattle ; Elephantiasis, Filarial - parasitology ; Elephantiasis, Filarial - pathology ; Elephantiasis, Filarial - therapy ; Females ; Humans ; Immunology ; Infections ; Males ; Morphology ; Mortality ; Mosquitoes ; Nematodes ; Nervous system ; Parasites ; Parasitic diseases ; Proteins ; Reproductive system ; Setaria Nematode ; Setariasis - epidemiology ; Setariasis - parasitology ; Setariasis - pathology ; Studies ; Tropical diseases ; Worms</subject><ispartof>Journal of helminthology, 2016-03, Vol.90 (2), p.129-138</ispartof><rights>Copyright © Cambridge University Press 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c509t-6299a0d099204d9d5e73ed3da8b5ffbcccdb25b2fa10968cc5edb0269f6958e13</citedby><cites>FETCH-LOGICAL-c509t-6299a0d099204d9d5e73ed3da8b5ffbcccdb25b2fa10968cc5edb0269f6958e13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0022149X15000309/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,776,780,27901,27902,55603</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25924635$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Perumal, A.N.I.</creatorcontrib><creatorcontrib>Gunawardene, Y.I.N.S.</creatorcontrib><creatorcontrib>Dassanayake, R.S.</creatorcontrib><title>Setaria digitata in advancing our knowledge of human lymphatic filariasis</title><title>Journal of helminthology</title><addtitle>J. Helminthol</addtitle><description>Setaria digitata is a filarial parasite that causes fatal cerebrospinal nematodiasis in goats, sheep and horses, resulting in substantial economic losses in animal husbandry in the tropics. Due to its close resemblance to Wuchereria bancrofti, this nematode is also frequently used as a model organism to study human lymphatic filariasis. 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Helminthol</addtitle><date>2016-03-01</date><risdate>2016</risdate><volume>90</volume><issue>2</issue><spage>129</spage><epage>138</epage><pages>129-138</pages><issn>0022-149X</issn><eissn>1475-2697</eissn><abstract>Setaria digitata is a filarial parasite that causes fatal cerebrospinal nematodiasis in goats, sheep and horses, resulting in substantial economic losses in animal husbandry in the tropics. Due to its close resemblance to Wuchereria bancrofti, this nematode is also frequently used as a model organism to study human lymphatic filariasis. This review highlights numerous insights into the morphological, histological, biochemical, immunological and genetic aspects of S. digitata that have broadened our understanding towards the control and eradication of filarial diseases.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>25924635</pmid><doi>10.1017/S0022149X15000309</doi><tpages>10</tpages></addata></record> |
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subjects | Animals Antigens Biology Cattle Elephantiasis, Filarial - parasitology Elephantiasis, Filarial - pathology Elephantiasis, Filarial - therapy Females Humans Immunology Infections Males Morphology Mortality Mosquitoes Nematodes Nervous system Parasites Parasitic diseases Proteins Reproductive system Setaria Nematode Setariasis - epidemiology Setariasis - parasitology Setariasis - pathology Studies Tropical diseases Worms |
title | Setaria digitata in advancing our knowledge of human lymphatic filariasis |
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