Setaria digitata in advancing our knowledge of human lymphatic filariasis

Setaria digitata in advancing our knowledge of human lymphatic filariasis

Setaria digitata is a filarial parasite that causes fatal cerebrospinal nematodiasis in goats, sheep and horses, resulting in substantial economic losses in animal husbandry in the tropics. Due to its close resemblance to Wuchereria bancrofti, this nematode is also frequently used as a model organis...

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Veröffentlicht in:Journal of helminthology 2016-03, Vol.90 (2), p.129-138
Hauptverfasser: Perumal, A.N.I., Gunawardene, Y.I.N.S., Dassanayake, R.S.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antigens
Biology
Cattle
Elephantiasis, Filarial - parasitology
Elephantiasis, Filarial - pathology
Elephantiasis, Filarial - therapy
Females
Humans
Immunology
Infections
Males
Morphology
Mortality
Mosquitoes
Nematodes
Nervous system
Parasites
Parasitic diseases
Proteins
Reproductive system
Setaria Nematode
Setariasis - epidemiology
Setariasis - parasitology
Setariasis - pathology
Studies
Tropical diseases
Worms
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Beschreibung
Zusammenfassung:Setaria digitata is a filarial parasite that causes fatal cerebrospinal nematodiasis in goats, sheep and horses, resulting in substantial economic losses in animal husbandry in the tropics. Due to its close resemblance to Wuchereria bancrofti, this nematode is also frequently used as a model organism to study human lymphatic filariasis. This review highlights numerous insights into the morphological, histological, biochemical, immunological and genetic aspects of S. digitata that have broadened our understanding towards the control and eradication of filarial diseases.
ISSN:0022-149X
1475-2697
DOI:10.1017/S0022149X15000309