Reference values of regional cerebral oxygen saturation during the first 3 days of life in preterm neonates

Background: Currently, reliable reference values of regional cerebral oxygen saturation (rScO 2 ) for different gestational age (GA) groups are lacking, which hampers the implementation of near-infrared spectroscopy (NIRS) alongside monitoring arterial oxygen saturation (SaO 2 ) and blood pressure i...

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Veröffentlicht in:	Pediatric research 2016-01, Vol.79 (1), p.55-64
Hauptverfasser:	Alderliesten, Thomas, Dix, Laura, Baerts, Wim, Caicedo, Alexander, van Huffel, Sabine, Naulaers, Gunnar, Groenendaal, Floris, van Bel, Frank, Lemmers, Petra
Format:	Artikel
Sprache:	eng
Schlagworte:	692/700/1720/3185 692/700/1720/3186 Body Size Brain Chemistry clinical-investigation Female Gestational Age Humans Infant, Newborn Infant, Premature - metabolism Infant, Small for Gestational Age Intensive Care Units, Neonatal Linear Models Male Medicine & Public Health Monitoring, Physiologic - instrumentation Oximetry - instrumentation Oxygen - analysis Pediatric Surgery Pediatrics Reference Values Sex Characteristics Spectroscopy, Near-Infrared - instrumentation
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Zusammenfassung:	Background: Currently, reliable reference values of regional cerebral oxygen saturation (rScO 2 ) for different gestational age (GA) groups are lacking, which hampers the implementation of near-infrared spectroscopy (NIRS) alongside monitoring arterial oxygen saturation (SaO 2 ) and blood pressure in neonatal intensive care. The aim of this study was to provide reference values for rScO 2 and cerebral fractional tissue oxygen extraction (cFTOE; (SaO 2 − rScO 2 )/SaO 2 ) for small adult and neonatal NIRS sensors. Methods: In this study, 999 infants born preterm (GA
ISSN:	0031-3998 1530-0447
DOI:	10.1038/pr.2015.186