MY APPROACH to genetic testing in cardiology practice

[...]currently the interpretation of genetic tests is subjected to the complexity of the molecular basis of LQTS, and, even more than before, a comprehensive clinical approach along with pre- and post-genetic counseling is necessary to assess each variant effect and weight in the patient phenotype, as well as which variant(s) to be tested for in the proband's first-degree relatives to identify at-risk family members.