William E. Paul, M.D. (1936–2015)

[...]core effort on IL-4 and Th2 cell biology, Bill made seminal contributions to our understanding of how immunoglobulin production and class selection are controlled, the basis for MHC-restricted recognition of antigen by T cells, the regulation of cell proliferation and clonality in lymphopenic a...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2015-10, Vol.43 (4), p.617-619
Hauptverfasser:	Germain, Ronald N., Fowlkes, B.J., Samelson, Lawrence E., Leonard, Warren J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome AIDS Allergy and Immunology - history Antigens Awards & honors Biology Careers Cytokines History, 20th Century History, 21st Century HIV Human immunodeficiency virus Humans Immune system Immunology Interleukin-4 - history Laboratories Lymphocytes Male National Institute of Allergy and Infectious Diseases (U.S.) - history Paul Periodicals as Topic - history Scientists Societies, Scientific - history Studies Th2 Cells - immunology United States
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Beschreibung
Zusammenfassung:	[...]core effort on IL-4 and Th2 cell biology, Bill made seminal contributions to our understanding of how immunoglobulin production and class selection are controlled, the basis for MHC-restricted recognition of antigen by T cells, the regulation of cell proliferation and clonality in lymphopenic animals, and the role of mast cells and basophils in cytokine production. [...]Bill Paul was the scientist's scientist.
ISSN:	1074-7613 1097-4180
DOI:	10.1016/j.immuni.2015.10.006