Molecularly Defined Nanostructures Based on a Novel AAA-DDD Triple Hydrogen-Bonding Motif

A facile and flexible method for the synthesis of a new AAA–DDD triple hydrogen‐bonding motif is described. Polytopic supramolecular building blocks with precisely oriented AAA and DDD groups are thus accessible in few steps. These building blocks were used for the assembly of large macrocycles featuring four AAA–DDD interactions and a macrobicyclic complex with a total of six AAA–DDD interactions. Made to connect: A new synthetic method provides facile access to supramolecular building blocks with multiple AAA or DDD groups (A=acceptor, D=donor). The components assemble by forming stable AAA–DDD triple hydrogen bonds to give macrocycles or a macrobicyclic complex (see scheme).