Chiral Analysis Using Broadband Rotational Spectroscopy
broadband microwave spectroscopy is a proven tool to precisely determine molecular properties of gas-phase molecules. Recent developments make it applicable to investigate chiral molecules. Enantiomers can be differentiated, and the enantiomeric excess and, indirectly, the absolute configuration can...
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Veröffentlicht in: | The journal of physical chemistry letters 2016-01, Vol.7 (2), p.341-350 |
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Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | broadband microwave spectroscopy is a proven tool to precisely determine molecular properties of gas-phase molecules. Recent developments make it applicable to investigate chiral molecules. Enantiomers can be differentiated, and the enantiomeric excess and, indirectly, the absolute configuration can be determined in a molecule-selective manner. The resonant character and high resolution of rotational spectroscopy provide a unique mixture compatibility. Future directions, such as extending the technique to chemical analysis, are discussed. |
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ISSN: | 1948-7185 1948-7185 |
DOI: | 10.1021/acs.jpclett.5b02443 |