Liver Transplantation for Biliary Atresia: Is There a Difference in Outcome for Infants?

Liver Transplantation for Biliary Atresia: Is There a Difference in Outcome for Infants?

OBJECTIVES:Liver transplantation (LT) in children with biliary atresia (BA) is often performed because of poor bile drainage, complications of biliary cirrhosis, or recurrent cholangitis. Poor bile drainage after a Kasai hepatoportoenterostomy is the primary driver for LT in infancy. The aim of the...

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Veröffentlicht in:Journal of pediatric gastroenterology and nutrition 2016-02, Vol.62 (2), p.220-225
Hauptverfasser: Arnon, Ronen, Annunziato, Rachel A, D’Amelio, Guiseppe, Chu, Jaime, Shneider, Benjamin L
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Age Factors
Bile Ducts - pathology
Bile Ducts - surgery
Biliary Atresia - complications
Biliary Atresia - surgery
Child
Child, Preschool
Cholangitis - etiology
Cholangitis - surgery
Female
Graft Survival
Humans
Infant
Liver Transplantation - mortality
Male
Portoenterostomy, Hepatic - adverse effects
Prognosis
Risk Factors
Survival Analysis
Treatment Outcome
Waiting Lists
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Zusammenfassung:OBJECTIVES:Liver transplantation (LT) in children with biliary atresia (BA) is often performed because of poor bile drainage, complications of biliary cirrhosis, or recurrent cholangitis. Poor bile drainage after a Kasai hepatoportoenterostomy is the primary driver for LT in infancy. The aim of the present study was to compare the clinical characteristics and outcome of first isolated liver transplantation for infants with BA who underwent transplant before 2 years of age (transplanted at infancy [TAI]) with children transplanted later in life (age 2–
ISSN:0277-2116
1536-4801
DOI:10.1097/MPG.0000000000000986