Relation Between Family History of Premature Coronary Artery Disease and the Risk of Death in Patients With Coronary Artery Disease

Relation Between Family History of Premature Coronary Artery Disease and the Risk of Death in Patients With Coronary Artery Disease

Family history (FHx) of premature coronary artery disease (CAD) is a risk factor for development of incident cardiovascular disease. However the association between FHx and outcomes in patients with established CAD is unclear. We followed 84,373 patients with angiographic CAD enrolled in the inclusi...

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Veröffentlicht in:The American journal of cardiology 2016-02, Vol.117 (3), p.353-358
Hauptverfasser: Abdi-Ali, Ahmed, MD, Shaheen, AbdelAziz, MD, Southern, Danielle, MSc, Zhang, Mei, MSc, Knudtson, Merril, MD, White, James, MD, Graham, Michelle, MD, James, Mathew T., MD, PhD, Wilton, Stephen B., MD, MSc
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Alberta - epidemiology
Angina pectoris
Cardiology
Cardiovascular
Cardiovascular disease
Coronary Angiography
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - genetics
Coronary Artery Disease - mortality
Family
Female
Follow-Up Studies
Forecasting
Genetic Predisposition to Disease
Heart attacks
Humans
Male
Middle Aged
Mortality
Pedigree
Prognosis
Prospective Studies
Registries
Risk Assessment
Risk Factors
Survival Rate - trends
Time Factors
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Zusammenfassung:Family history (FHx) of premature coronary artery disease (CAD) is a risk factor for development of incident cardiovascular disease. However the association between FHx and outcomes in patients with established CAD is unclear. We followed 84,373 patients with angiographic CAD enrolled in the inclusive Alberta Provincial Project for Outcomes Assessment in Coronary Heart Disease registry between April 2002 and March 2013. Overall, 25,566 (30%) self-reported an FHx of CAD, defined as a first-degree relative with premature CAD (men, age
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2015.11.008