A New Trinor-guaiane Sesquiterpene from an Indonesian Soft Coral Anthelia sp

A New Trinor-guaiane Sesquiterpene from an Indonesian Soft Coral Anthelia sp

A new trinor-guaiane sesquiterpene has been isolated from an Indonesian soft coral Anthelia sp. The planar structure, possessing an octahydroazulene skeleton, and relative stereochemistry were established by analyzing 1D and 2D NMR data, including NOE experiments. Its absolute stereochemistry was el...

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Veröffentlicht in:Natural product communications 2015-11, Vol.10 (11), p.1907-1910
Hauptverfasser: Hanif, Novriyandi, Murni, Anggia, Yamauchi, Marie, Higashi, Masahiro, Tanaka, Junichi
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Anthozoa - chemistry
Magnetic Resonance Spectroscopy
Molecular Structure
Sesquiterpenes, Guaiane - chemistry
Sesquiterpenes, Guaiane - isolation & purification
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Zusammenfassung:A new trinor-guaiane sesquiterpene has been isolated from an Indonesian soft coral Anthelia sp. The planar structure, possessing an octahydroazulene skeleton, and relative stereochemistry were established by analyzing 1D and 2D NMR data, including NOE experiments. Its absolute stereochemistry was elucidated to be 1S, 4S, 7R, and 10R by comparing observed and calculated optical rotation values. The new compound showed weak cytotoxicity against NBT-T2 cells.
ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X1501001124