The role of vitamin D in post-thyroidectomy hypocalcemia: Still an enigma

Background There is conflicting evidence regarding the role of vitamin D deficiency in the development of post-thyroidectomy hypocalcemia. Recent reports show postoperative parathormone (PTH) is unreliable in predicting post-thyroidectomy hypocalcemia in vitamin D deficient patients. We conducted th...

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Veröffentlicht in:Surgery 2016-02, Vol.159 (2), p.532-538
Hauptverfasser: Cherian, Anish Jacob, MCh, Ponraj, Sam, MS, Gowri S, Mahasampath, MSc, Ramakant, Pooja, MCh, Paul, Thomas V., PhD, Abraham, Deepak Thomas, PhD, Paul, M.J., MS
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Sprache:eng
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Zusammenfassung:Background There is conflicting evidence regarding the role of vitamin D deficiency in the development of post-thyroidectomy hypocalcemia. Recent reports show postoperative parathormone (PTH) is unreliable in predicting post-thyroidectomy hypocalcemia in vitamin D deficient patients. We conducted this study to analyze the role of vitamin D status in the development of post-thyroidectomy hypocalcemia and to evaluate its effect on the predictability of PTH as a marker for post-thyroidectomy hypocalcemia. Method A retrospective review of prospectively collected data of patients undergoing thyroidectomy between August 2007 to September 2013 ( n  = 150) was performed. Results of preoperative calcium, albumin, vitamin D, PTH and postoperative calcium, albumin, and PTH were collated. Patients were divided into 2 groups based on their vitamin D status: group A, vitamin D ≥ 20 ng/mL and group B, vitamin D 
ISSN:0039-6060
1532-7361
DOI:10.1016/j.surg.2015.08.014