Mycophenolate Mofetil Therapy in Refractory Inflammatory Eye Disease

To study the efficacy and incidence of treatment-related side effects of mycophenolate mofetil (MMF) therapy in patients with noninfectious inflammatory eye diseases. Retrospective cohort study of 27 Chilean patients treated for noninfectious inflammatory eye diseases using MMF therapy over a 10-yea...

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Veröffentlicht in:Journal of ocular pharmacology and therapeutics 2016-01, Vol.32 (1), p.55-61
Hauptverfasser: Cuchacovich, Miguel, Solanes, Federica, Perez, Claudio, Verdaguer, Juan Ignacio, Verdaguer, Juan, Castiglione, Enzo, Carpentier, Cristian, Traipe, Leonidas, Villarroel, Francisco
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Sprache:eng
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Zusammenfassung:To study the efficacy and incidence of treatment-related side effects of mycophenolate mofetil (MMF) therapy in patients with noninfectious inflammatory eye diseases. Retrospective cohort study of 27 Chilean patients treated for noninfectious inflammatory eye diseases using MMF therapy over a 10-year period. Main outcome measures were: ability to control ocular inflammation and to taper prednisone to ≤10 mg daily (treatment success); incidence of treatment-related side effects. The proportion of patients with sustained control of inflammation was 81.48% at 6 months. Additionally 55.56% and 22.22% of patients succeeded in tapering their prednisone to 5-10 mg/day and
ISSN:1080-7683
1557-7732
DOI:10.1089/jop.2015.0044