The impact of non-alcoholic fatty liver disease on incident type 2 diabetes mellitus in non-overweight individuals

Background & Aims The aim of this study was to evaluate the impact of non‐alcoholic fatty liver disease (NAFLD) on incident type 2 diabetes mellitus (T2DM) in non‐overweight individuals with NAFLD. Methods A population‐based retrospective cohort study of 4629 participants who were enrolled in a...

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Veröffentlicht in:	Liver international 2016-02, Vol.36 (2), p.275-283
Hauptverfasser:	Fukuda, Takuya, Hamaguchi, Masahide, Kojima, Takao, Hashimoto, Yoshitaka, Ohbora, Akihiro, Kato, Takahiro, Nakamura, Naoto, Fukui, Michiaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Body Mass Index cohort study diabetes Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - etiology epidemiology Female Humans Incidence Japan - epidemiology Liver - diagnostic imaging liver disease Male Middle Aged non-alcoholic fatty liver Non-alcoholic Fatty Liver Disease - complications Non-alcoholic Fatty Liver Disease - diagnosis Non-alcoholic Fatty Liver Disease - epidemiology Proportional Hazards Models Retrospective Studies Risk Factors Ultrasonography
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Zusammenfassung:	Background & Aims The aim of this study was to evaluate the impact of non‐alcoholic fatty liver disease (NAFLD) on incident type 2 diabetes mellitus (T2DM) in non‐overweight individuals with NAFLD. Methods A population‐based retrospective cohort study of 4629 participants who were enrolled in a health check‐up programme for more than 10 years. A standardized questionnaire and abdominal ultrasonography were used to diagnose NAFLD. A cut‐off point of BMI 23 kg/m2 was used to define overweight (≥23.0 kg/m2) or non‐overweight (
ISSN:	1478-3223 1478-3231
DOI:	10.1111/liv.12912