Abnormal degree centrality in neurologically asymptomatic patients with end-stage renal disease: A resting-state fMRI study

Highlights • Abnormal intrinsic dysconnectivity pattern of whole-brain functional networks occurs in end-stage renal disease (ESRD) patients using resting-state fMRI. • ESRD patients have decreased functional connectivity in the left inferior parietal and left precuneus within the brain network. • E...

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Veröffentlicht in:	Clinical neurophysiology 2016-01, Vol.127 (1), p.602-609
Hauptverfasser:	Li, Shumei, Ma, Xiaofen, Huang, Ruiwang, Li, Meng, Tian, Junzhang, Wen, Hua, Lin, Chulan, Wang, Tianyue, Zhan, Wenfeng, Fang, Jin, Jiang, Guihua
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Asymptomatic Diseases Brain - physiopathology Degree centrality End-stage renal disease (ESRD) Female Functional magnetic resonance imaging (fMRI) Humans Kidney Failure, Chronic - diagnosis Kidney Failure, Chronic - physiopathology Magnetic Resonance Imaging - methods Male Middle Aged Nerve Net - physiopathology Neurology Rest - physiology Whole-brain functional networks Young Adult
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Zusammenfassung:	Highlights • Abnormal intrinsic dysconnectivity pattern of whole-brain functional networks occurs in end-stage renal disease (ESRD) patients using resting-state fMRI. • ESRD patients have decreased functional connectivity in the left inferior parietal and left precuneus within the brain network. • ESRD patients have increased connectivity in depression-related regions including bilateral inferior frontal gyrus and right superior temporal gyrus.
ISSN:	1388-2457 1872-8952
DOI:	10.1016/j.clinph.2015.06.022