Systematic review with meta‐analysis: long‐term outcomes of faecal microbiota transplantation for Clostridium difficile infection

Systematic review with meta‐analysis: long‐term outcomes of faecal microbiota transplantation for Clostridium difficile infection

Summary Background Clostridium difficile infection is a major cause of nosocomial diarrhoea. Aim To evaluate long‐term (≥90 days) efficacy and safety of faecal microbiota transplantation for C. difficile infection and explore the factors affecting the faecal microbiota transplantation outcomes. Meth...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Alimentary pharmacology & therapeutics 2016-02, Vol.43 (4), p.445-457
Hauptverfasser: Li, Y.‐T., Cai, H.‐F., Wang, Z.‐H., Xu, J., Fang, J.‐Y.
Format: Artikel
Sprache:eng
Schlagworte:
Age Factors
Clostridium difficile
Clostridium Infections - therapy
Fecal Microbiota Transplantation - adverse effects
Fecal Microbiota Transplantation - methods
Feces
Humans
Observational Studies as Topic
Recurrence
Risk Factors
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Summary Background Clostridium difficile infection is a major cause of nosocomial diarrhoea. Aim To evaluate long‐term (≥90 days) efficacy and safety of faecal microbiota transplantation for C. difficile infection and explore the factors affecting the faecal microbiota transplantation outcomes. Methods MEDLINE, the Cochrane Library and EMBASE were searched and only observational studies that utilised faecal microbiota transplantation for C. difficile infection with long‐term follow‐up duration (≥90 days) were included. Primary cure rate, overall recurrence rate and early (
ISSN:0269-2813
1365-2036
DOI:10.1111/apt.13492