Metastasized Leydig cell tumor in a dog

We present the clinical findings, diagnosis and treatment of an 11-year old intact male Fox Terrier with a malignant Leydig cell tumor of the right testicle, which metastasized to the skeletal musculature of the left hind limb. The primary tumor and the metastasis were resected with narrow margins....

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Veröffentlicht in:	Schweizer Archiv für Tierheilkunde 2015-02, Vol.157 (2), p.111-115
Hauptverfasser:	Togni, A, Rütten, M, Bley, C Rohrer, Hurter, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Metronomic - veterinary Angiogenesis Inhibitors - administration & dosage Animals Antineoplastic Agents, Alkylating - administration & dosage Chemotherapy, Adjuvant - veterinary Cyclophosphamide - administration & dosage Dog Diseases - diagnosis Dog Diseases - pathology Dog Diseases - therapy Dogs Euthanasia, Animal Fatal Outcome Hindlimb Leydig Cell Tumor - diagnosis Leydig Cell Tumor - secondary Leydig Cell Tumor - therapy Leydig Cell Tumor - veterinary Lung Neoplasms - diagnosis Lung Neoplasms - secondary Lung Neoplasms - veterinary Male Muscle Neoplasms - diagnosis Muscle Neoplasms - secondary Muscle Neoplasms - therapy Muscle Neoplasms - veterinary Neoplasm Recurrence, Local - diagnosis Neoplasm Recurrence, Local - therapy Neoplasm Recurrence, Local - veterinary Testicular Neoplasms - diagnosis Testicular Neoplasms - pathology Testicular Neoplasms - therapy Testicular Neoplasms - veterinary Thalidomide - administration & dosage
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Beschreibung
Zusammenfassung:	We present the clinical findings, diagnosis and treatment of an 11-year old intact male Fox Terrier with a malignant Leydig cell tumor of the right testicle, which metastasized to the skeletal musculature of the left hind limb. The primary tumor and the metastasis were resected with narrow margins. The dog was treated with metronomic chemotherapy using thalidomid and dyclophosphamide. Local recurrence at the site of the metastasis and a pulmonary metastasis were present 30 months after surgery. The dog was euthanized.
ISSN:	0036-7281 1664-2848
DOI:	10.17236/sat00010