Serum levels of ET-1, M30, and angiopoietins-1 and -2 in HELLP syndrome and preeclampsia compared to controls

Purpose We aimed to compare the serum levels of ET-1, M30, and Angs-1 and -2 in patients with preeclampsia or HELLP syndrome, and normal controls. Methods In this cross-sectional study of 74 pregnant women, serum levels of ET-1, M30, and Angs-1 and -2 were measured in preeclamptic patients with or without HELLP syndrome. 74 pregnant women; 37 had healthy pregnancies, 25 had preeclampsia (PE), and 12 had HELLP syndrome. Results The age, body mass index, gravidity, and parity of patients with normal pregnancy, PE, and HELLP syndrome were comparable ( p > 0.05). In HELLP syndrome, compared to healthy or preeclamptic pregnancies, platelet count was lower ( p