Phytoconstituents and antimicrobial activity of Melaleuca leucadendron leaf essential oil from Venezuela

The essential oil composition of Venezuelan Melaleuca leucadendron leaves was determined. The oil was extracted by hydrodistillation and analyzed by HRGC and GC-MS. Among the 44 constituents identified, 1,8-cineole (38.4%), nerolidol (28.7%), alloaromadendrene (14.4%) and alpha -terpineol (12.6%) we...

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Veröffentlicht in:Ciencia (Maracaibo, Venezuela) Venezuela), 1998-08, Vol.6 (2), p.123-128
Hauptverfasser: De Colmenares, NG, De Rodriguez, GO, Prieto, A, Crescente, O, Cabrera, L
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Sprache:eng ; spa
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Zusammenfassung:The essential oil composition of Venezuelan Melaleuca leucadendron leaves was determined. The oil was extracted by hydrodistillation and analyzed by HRGC and GC-MS. Among the 44 constituents identified, 1,8-cineole (38.4%), nerolidol (28.7%), alloaromadendrene (14.4%) and alpha -terpineol (12.6%) were the most abundant. The 1,8-cineole content was an indication that this essential oil belongs to the chemotype I. The essential oil was active against Bacillus cereus and Staphylococcus aureus, but was inactive against Escherichia coli and Pseudomonas aeruginosa. It also showed toxicity in the brine shrimp (Artemia salina) lethality test (LC50 (24 h) = 22.25 mu g/ml).
ISSN:1315-2076