Antifungal activity of some Bignoniaceae found in Malaysia

Antifungal activity of some Bignoniaceae found in Malaysia

The dichloromethane extracts of Tabebuia chrysantha, Oroxylum indicum, Fernandoa adenophylla and Jacaranda filicifolia display antifungal activity against dermatophytes and wood rot fungi. The activity is probably due mainly to lapachol and β‐lapachone which were shown to be present in these plant e...

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Veröffentlicht in:Phytotherapy research 1998-08, Vol.12 (5), p.331-334
Hauptverfasser: Ali, Rasadah Mat, Houghton, Peter J., Hoo, T. S.
Format: Artikel
Sprache:eng
Schlagworte:
antifungal activity
b-Lapachone
Bignoniaceae
Biological and medical sciences
Fernandoa adenophylla
General pharmacology
lapachol
Malaysia
Medical sciences
Oroxylum indicum
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Tabebuia chrysantha
β-lapachone
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Zusammenfassung:The dichloromethane extracts of Tabebuia chrysantha, Oroxylum indicum, Fernandoa adenophylla and Jacaranda filicifolia display antifungal activity against dermatophytes and wood rot fungi. The activity is probably due mainly to lapachol and β‐lapachone which were shown to be present in these plant extracts. Microscopical study has shown that these extracts inhibit the development of mycelium and conidia in the filamentous fungi. © 1998 John Wiley & Sons, Ltd.
ISSN:0951-418X
1099-1573
DOI:10.1002/(SICI)1099-1573(199808)12:5<331::AID-PTR305>3.0.CO;2-W