Expression of Hepatitis C Virus Proteins Interferes with the Antiviral Action of Interferon Independently of PKR-Mediated Control of Protein Synthesis
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| Veröffentlicht in: | Journal of Virology 2000-06, Vol.74 (12), p.5587-5596 |
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| creator | François, C Duverlie, G Rebouillat, D Khorsi, H Castelain, S Blum, H E Gatignol, A Wychowski, C Moradpour, D Meurs, E F |
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| doi_str_mv | 10.1128/JVI.74.12.5587-5596.2000 |
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</description><identifier>ISSN: 0022-538X</identifier><identifier>EISSN: 1098-5514</identifier><identifier>DOI: 10.1128/JVI.74.12.5587-5596.2000</identifier><identifier>PMID: 10823866</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>2',5'-Oligoadenylate Synthetase - biosynthesis ; 2',5'-Oligoadenylate Synthetase - metabolism ; Antiviral Agents - antagonists & inhibitors ; Antiviral Agents - pharmacology ; Cytoplasm - chemistry ; Cytoplasm - enzymology ; eIF-2 Kinase - antagonists & inhibitors ; eIF-2 Kinase - biosynthesis ; eIF-2 Kinase - metabolism ; eIF2^a protein ; Encephalomyocarditis virus ; Encephalomyocarditis virus - drug effects ; Encephalomyocarditis virus - physiology ; Endoplasmic Reticulum - chemistry ; Eukaryotic Initiation Factor-2 - metabolism ; Gene Expression - drug effects ; Gene Expression Regulation, Viral - drug effects ; Hepacivirus - drug effects ; Hepacivirus - genetics ; Hepacivirus - metabolism ; Hepatitis C virus ; Humans ; Interferons - antagonists & inhibitors ; Interferons - pharmacology ; Microscopy, Confocal ; NS5A protein ; Phosphorylation - drug effects ; Poly I-C - pharmacology ; Polyproteins - biosynthesis ; Polyproteins - genetics ; Polyproteins - metabolism ; Protein Biosynthesis - drug effects ; Tetracycline - pharmacology ; Tumor Cells, Cultured ; Viral Nonstructural Proteins - biosynthesis ; Viral Nonstructural Proteins - genetics ; Viral Nonstructural Proteins - metabolism ; Viral Proteins - biosynthesis ; Viral Proteins - genetics ; Viral Proteins - metabolism ; Virus-Cell Interactions</subject><ispartof>Journal of Virology, 2000-06, Vol.74 (12), p.5587-5596</ispartof><rights>Copyright © 2000, American Society for Microbiology 2000</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c473t-7a23c187ff3191981bd22f3295d01333625bdb8737ad7c2ac840efa33bc804d73</citedby><cites>FETCH-LOGICAL-c473t-7a23c187ff3191981bd22f3295d01333625bdb8737ad7c2ac840efa33bc804d73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC112046/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC112046/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10823866$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>François, C</creatorcontrib><creatorcontrib>Duverlie, G</creatorcontrib><creatorcontrib>Rebouillat, D</creatorcontrib><creatorcontrib>Khorsi, H</creatorcontrib><creatorcontrib>Castelain, S</creatorcontrib><creatorcontrib>Blum, H E</creatorcontrib><creatorcontrib>Gatignol, A</creatorcontrib><creatorcontrib>Wychowski, C</creatorcontrib><creatorcontrib>Moradpour, D</creatorcontrib><creatorcontrib>Meurs, E F</creatorcontrib><title>Expression of Hepatitis C Virus Proteins Interferes with the Antiviral Action of Interferon Independently of PKR-Mediated Control of Protein Synthesis</title><title>Journal of Virology</title><addtitle>J Virol</addtitle><description>Article Usage Stats
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</description><subject>2',5'-Oligoadenylate Synthetase - biosynthesis</subject><subject>2',5'-Oligoadenylate Synthetase - metabolism</subject><subject>Antiviral Agents - antagonists & inhibitors</subject><subject>Antiviral Agents - pharmacology</subject><subject>Cytoplasm - chemistry</subject><subject>Cytoplasm - enzymology</subject><subject>eIF-2 Kinase - antagonists & inhibitors</subject><subject>eIF-2 Kinase - biosynthesis</subject><subject>eIF-2 Kinase - metabolism</subject><subject>eIF2^a protein</subject><subject>Encephalomyocarditis virus</subject><subject>Encephalomyocarditis virus - drug effects</subject><subject>Encephalomyocarditis virus - physiology</subject><subject>Endoplasmic Reticulum - chemistry</subject><subject>Eukaryotic Initiation Factor-2 - metabolism</subject><subject>Gene Expression - drug effects</subject><subject>Gene Expression Regulation, Viral - drug effects</subject><subject>Hepacivirus - drug effects</subject><subject>Hepacivirus - genetics</subject><subject>Hepacivirus - metabolism</subject><subject>Hepatitis C virus</subject><subject>Humans</subject><subject>Interferons - antagonists & inhibitors</subject><subject>Interferons - pharmacology</subject><subject>Microscopy, Confocal</subject><subject>NS5A protein</subject><subject>Phosphorylation - drug effects</subject><subject>Poly I-C - pharmacology</subject><subject>Polyproteins - biosynthesis</subject><subject>Polyproteins - genetics</subject><subject>Polyproteins - metabolism</subject><subject>Protein Biosynthesis - drug effects</subject><subject>Tetracycline - pharmacology</subject><subject>Tumor Cells, Cultured</subject><subject>Viral Nonstructural Proteins - biosynthesis</subject><subject>Viral Nonstructural Proteins - genetics</subject><subject>Viral Nonstructural Proteins - metabolism</subject><subject>Viral Proteins - biosynthesis</subject><subject>Viral Proteins - genetics</subject><subject>Viral Proteins - metabolism</subject><subject>Virus-Cell Interactions</subject><issn>0022-538X</issn><issn>1098-5514</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1u1DAUhS0EotPCKyCLBbuk_kvsLFiMRqUdWkTFT8XOchKncZWxg-2ZMi_C8-KQAQ0rNrZ8_Z1z79UBAGKUY0zE-fu7dc5ZjkleFIJnRVGVOUEIPQELjCqRCpg9BQuECMkKKr6dgNMQHhDCjJXsOTjBSBAqynIBfl78GL0OwTgLXQev9KiiiSbAFbwzfhvgrXdRGxvg2kbtO51g-GhiD2Ov4dJGszNeDXDZxIPFHy691rbVo06HjcN--ru9_pR90K1RUbdw5Wz0bvhdn5vAz3ubbIMJL8CzTg1BvzzcZ-Dru4svq6vs5uPlerW8yRrGacy4IrTBgncdxRWuBK5bQjpKqqJFmFJakqJua8EpVy1viGoEQ7pTlNaNQKzl9Ay8nX3Hbb3RbZMmTdvI0ZuN8nvplJH__ljTy3u3kykGxMqkf3PQe_d9q0OUGxMaPQzKarcNkk9xEVH9F8S8YIhzkUAxg413IXjd_R0Go6mrkCl8yZnERE7hyyl8OYWfpK-OlzkSzmkn4PUM9Oa-fzReSxU28mFnjvzoL7SZuoM</recordid><startdate>20000601</startdate><enddate>20000601</enddate><creator>François, C</creator><creator>Duverlie, G</creator><creator>Rebouillat, D</creator><creator>Khorsi, H</creator><creator>Castelain, S</creator><creator>Blum, H E</creator><creator>Gatignol, A</creator><creator>Wychowski, C</creator><creator>Moradpour, D</creator><creator>Meurs, E F</creator><general>American Society for Microbiology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20000601</creationdate><title>Expression of Hepatitis C Virus Proteins Interferes with the Antiviral Action of Interferon Independently of PKR-Mediated Control of Protein Synthesis</title><author>François, C ; 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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>10823866</pmid><doi>10.1128/JVI.74.12.5587-5596.2000</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | 2',5'-Oligoadenylate Synthetase - biosynthesis 2',5'-Oligoadenylate Synthetase - metabolism Antiviral Agents - antagonists & inhibitors Antiviral Agents - pharmacology Cytoplasm - chemistry Cytoplasm - enzymology eIF-2 Kinase - antagonists & inhibitors eIF-2 Kinase - biosynthesis eIF-2 Kinase - metabolism eIF2^a protein Encephalomyocarditis virus Encephalomyocarditis virus - drug effects Encephalomyocarditis virus - physiology Endoplasmic Reticulum - chemistry Eukaryotic Initiation Factor-2 - metabolism Gene Expression - drug effects Gene Expression Regulation, Viral - drug effects Hepacivirus - drug effects Hepacivirus - genetics Hepacivirus - metabolism Hepatitis C virus Humans Interferons - antagonists & inhibitors Interferons - pharmacology Microscopy, Confocal NS5A protein Phosphorylation - drug effects Poly I-C - pharmacology Polyproteins - biosynthesis Polyproteins - genetics Polyproteins - metabolism Protein Biosynthesis - drug effects Tetracycline - pharmacology Tumor Cells, Cultured Viral Nonstructural Proteins - biosynthesis Viral Nonstructural Proteins - genetics Viral Nonstructural Proteins - metabolism Viral Proteins - biosynthesis Viral Proteins - genetics Viral Proteins - metabolism Virus-Cell Interactions |
| title | Expression of Hepatitis C Virus Proteins Interferes with the Antiviral Action of Interferon Independently of PKR-Mediated Control of Protein Synthesis |
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