Expression of Hepatitis C Virus Proteins Interferes with the Antiviral Action of Interferon Independently of PKR-Mediated Control of Protein Synthesis

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Veröffentlicht in:	Journal of Virology 2000-06, Vol.74 (12), p.5587-5596
Hauptverfasser:	François, C, Duverlie, G, Rebouillat, D, Khorsi, H, Castelain, S, Blum, H E, Gatignol, A, Wychowski, C, Moradpour, D, Meurs, E F
Format:	Artikel
Sprache:	eng
Schlagworte:	2',5'-Oligoadenylate Synthetase - biosynthesis 2',5'-Oligoadenylate Synthetase - metabolism Antiviral Agents - antagonists & inhibitors Antiviral Agents - pharmacology Cytoplasm - chemistry Cytoplasm - enzymology eIF-2 Kinase - antagonists & inhibitors eIF-2 Kinase - biosynthesis eIF-2 Kinase - metabolism eIF2^a protein Encephalomyocarditis virus Encephalomyocarditis virus - drug effects Encephalomyocarditis virus - physiology Endoplasmic Reticulum - chemistry Eukaryotic Initiation Factor-2 - metabolism Gene Expression - drug effects Gene Expression Regulation, Viral - drug effects Hepacivirus - drug effects Hepacivirus - genetics Hepacivirus - metabolism Hepatitis C virus Humans Interferons - antagonists & inhibitors Interferons - pharmacology Microscopy, Confocal NS5A protein Phosphorylation - drug effects Poly I-C - pharmacology Polyproteins - biosynthesis Polyproteins - genetics Polyproteins - metabolism Protein Biosynthesis - drug effects Tetracycline - pharmacology Tumor Cells, Cultured Viral Nonstructural Proteins - biosynthesis Viral Nonstructural Proteins - genetics Viral Nonstructural Proteins - metabolism Viral Proteins - biosynthesis Viral Proteins - genetics Viral Proteins - metabolism Virus-Cell Interactions
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Zusammenfassung:	Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue JVI About JVI Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy JVI RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0022-538X Online ISSN: 1098-5514 Copyright © 2014 by the American Society for Microbiology. For an alternate route to JVI .asm.org, visit: JVI
ISSN:	0022-538X 1098-5514
DOI:	10.1128/JVI.74.12.5587-5596.2000