MMP-9 gene polymorphisms (rs3918242, rs3918254 and rs4810482) and the risk of psoriasis vulgaris: No evidence for associations in a Chinese Han population

Highlights • The serum MMP-9 levels in psoriasis were significantly higher than that in controls. • This is the first study investigating the association of MMP-9 polymorphisms with psoriasis risk. • There was not any association of MMP-9 polymorphisms with susceptibility to psoriasis vulgaris....

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Veröffentlicht in:	Immunology letters 2015-12, Vol.168 (2), p.343-348
Hauptverfasser:	Liang, Jingyao, Zhao, Tian, Yang, Juan, Li, Wei, Zhang, Fang, Zhang, Sanquan, Huang, Zhenming, Lin, Rihua, Zhang, Xibao
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Alleles Allergy and Immunology Asian Continental Ancestry Group - genetics Child China Female Gene Frequency Genetic Predisposition to Disease - ethnology Genetic Predisposition to Disease - genetics Genotype Haplotypes Humans Male Matrix Metalloproteinase 9 - blood Matrix Metalloproteinase 9 - genetics Middle Aged MMP-9 Polymerase Chain Reaction Polymorphism, Single Nucleotide Psoriasis Psoriasis - enzymology Psoriasis - ethnology Psoriasis - genetics Risk Risk Factors Single nucleotide polymorphisms Young Adult
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Zusammenfassung:	Highlights • The serum MMP-9 levels in psoriasis were significantly higher than that in controls. • This is the first study investigating the association of MMP-9 polymorphisms with psoriasis risk. • There was not any association of MMP-9 polymorphisms with susceptibility to psoriasis vulgaris.
ISSN:	0165-2478 1879-0542
DOI:	10.1016/j.imlet.2015.11.003