A French monitoring programme for determining ochratoxin A occurrence in pig kidneys

Ochratoxin A is a carcinogen and nephrotoxin which can enter the food chain resulting in human exposure. As pig herds are exposed to ochratoxin A through their feed, their kidneys, livers and pork meat are considered as a possible route of exposure for humans. France, an important producer of pork a...

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Veröffentlicht in:Natural toxins 1999, Vol.7 (4), p.167-173
Hauptverfasser: Dragacci, S., Grosso, F., Bire, R., Fremy, J. M., Coulon, S.
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Sprache:eng
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Zusammenfassung:Ochratoxin A is a carcinogen and nephrotoxin which can enter the food chain resulting in human exposure. As pig herds are exposed to ochratoxin A through their feed, their kidneys, livers and pork meat are considered as a possible route of exposure for humans. France, an important producer of pork and pork products, set up a national monitoring programme which included the training of six routine public laboratories in the analysis of ochratoxin A using an immunoaffinity step followed by a HPLC‐fluorimetric detection. The programme randomly sampled 300 healthy and 100 nephropathic pig kidneys in 1997 and 710 healthy pig kidneys in 1998. Less than 10 % of samples were significantly contaminated by ochratoxin A : in the 1997 survey, 1 % of samples contained 0.40–1.40 µg kg−1 of ochratoxin A and in the 1998 survey 7.6 % exhibited ochratoxin A levels in the range 0.5–5 µg kg−1. In the case of nephropathic kidneys, only traces of ochratoxin A (0.16 to 0.48 µg kg−1) were detected in six samples out of 100. Even if not a major route of exposure for humans, pigs are clearly exposed to this mycotoxin and monitoring of pork products and of feed for swine is necessary. Copyright © 1999 John Wiley & Sons, Ltd.
ISSN:1056-9014
1522-7189
DOI:10.1002/(SICI)1522-7189(199907/08)7:4<167::AID-NT55>3.0.CO;2-Q