Influences of exercise on myocardic ICAM-1 expression and cardiac ultrastructure in rats

Observation of myocardic ICAM-1 expression and cardiac ultra structure in rats was made through establishing different loads of the rat's exercise model. The result revealed that in normal training group, the yocardium physiologic hypertrophy was adapted to aerobic metabolic and ICAM-1 expression was negative. But in the overload training group, the myocardium took pathological change and ICAM-1 expression was positive. Myocardium ICAM-1 positive expression rate had a positive correlations between both left ventricle weight and heart coefficient. The results indicated that ICAm-1 might be regarded as an index both for overload training and for discerning between physiologic and pathologic cardiac hypertrophy.