Determinants of brain-derived neurotrophic factor (BDNF) in umbilical cord and maternal serum

Determinants of brain-derived neurotrophic factor (BDNF) in umbilical cord and maternal serum

Highlights • The origin of circulating maternal and umbilical cord (UC) BDNF remains unresolved. • BDNF traffic between mother and fetus is unlikely. • Mode of delivery and gestational age are determinants of UC-BDNF. • Gestational age is the only determinant of maternal BDNF concentration. • BDNF m...

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Veröffentlicht in:Psychoneuroendocrinology 2016-01, Vol.63, p.191-197
Hauptverfasser: Flöck, A, Weber, S.K, Ferrari, N, Fietz, C, Graf, C, Fimmers, R, Gembruch, U, Merz, W.M
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Brain-Derived Neurotrophic Factor - blood
Cross-Sectional Studies
Delivery, Obstetric - methods
Endocrinology & Metabolism
Female
Fetal Blood - metabolism
Gestational Age
Humans
Infant, Newborn
Male
Mothers
Pregnancy - blood
Psychiatry
Umbilical Cord - metabolism
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Beschreibung
Zusammenfassung:Highlights • The origin of circulating maternal and umbilical cord (UC) BDNF remains unresolved. • BDNF traffic between mother and fetus is unlikely. • Mode of delivery and gestational age are determinants of UC-BDNF. • Gestational age is the only determinant of maternal BDNF concentration. • BDNF may be involved in the neurohormonal cascade of parturition.
ISSN:0306-4530
1873-3360
DOI:10.1016/j.psyneuen.2015.09.028