Influenza vaccine effectiveness against hospitalisation with influenza in adults in Australia in 2014

Highlights • Between April and November 2014, 1692 adult patients were admitted with influenza to a sentinel hospital network in Australia. • Vaccine effectiveness was estimated from 1283 patients with influenza and 1116 test negative patients where vaccination status was ascertained. • Vaccination...

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Veröffentlicht in:	Vaccine 2015-12, Vol.33 (51), p.7352-7356
Hauptverfasser:	Cheng, Allen C, Kotsimbos, Tom, Kelly, Paul M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Adults Age Aged Aged, 80 and over Allergy and Immunology Australia - epidemiology Chronic illnesses Female Funding Hospitalisation Hospitalization Hospitals Humans Immunization Influenza Influenza A Virus, H1N1 Subtype - immunology Influenza vaccination Influenza Vaccines - administration & dosage Influenza Vaccines - immunology Influenza, Human - epidemiology Influenza, Human - pathology Influenza, Human - prevention & control Laboratories Male Medical records Middle Aged Morbidity Mortality Pregnancy Risk Assessment Seasons Studies Surveillance Test negative design Treatment Outcome Vaccine effectiveness Vaccines Young Adult
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Beschreibung
Zusammenfassung:	Highlights • Between April and November 2014, 1692 adult patients were admitted with influenza to a sentinel hospital network in Australia. • Vaccine effectiveness was estimated from 1283 patients with influenza and 1116 test negative patients where vaccination status was ascertained. • Vaccination was associated with a reduction in the risk of hospitalisation with influenza of 51.5% (41.6%, 59.7%, p < 0.001).
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2015.10.016