Post-explant visualization of thrombi in outflow grafts and their junction to a continuous-flow total artificial heart using a high-definition miniaturized camera

Post-explant visualization of thrombi in outflow grafts and their junction to a continuous-flow total artificial heart using a high-definition miniaturized camera

Post-explant evaluation of the continuous-flow total artificial heart in preclinical studies can be extremely challenging because of the device’s unique architecture. Determining the exact location of tissue regeneration, neointima formation, and thrombus is particularly important. In this report, w...

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Veröffentlicht in:Journal of artificial organs 2015-12, Vol.18 (4), p.354-357
Hauptverfasser: Karimov, Jamshid H., Horvath, David, Sunagawa, Gengo, Byram, Nicole, Moazami, Nader, Golding, Leonard A. R., Fukamachi, Kiyotaka
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biomedical Engineering and Bioengineering
Cardiac Surgery
Case Report
Cattle
Heart, Artificial
Male
Materials Testing
Medicine
Medicine & Public Health
Nephrology
Thrombosis - etiology
Thrombosis - pathology
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Zusammenfassung:Post-explant evaluation of the continuous-flow total artificial heart in preclinical studies can be extremely challenging because of the device’s unique architecture. Determining the exact location of tissue regeneration, neointima formation, and thrombus is particularly important. In this report, we describe our first successful experience with visualizing the Cleveland Clinic continuous-flow total artificial heart using a custom-made high-definition miniature camera.
ISSN:1434-7229
1619-0904
DOI:10.1007/s10047-015-0839-8