Short-term impact of fampridine on motor and cognitive functions, mood and quality of life among multiple sclerosis patients

Highlights • Fampridine is licensed to improve walking in all types of multiple sclerosis. • We examined fampridine's impact on various functions besides walking. • Fampridine seems to improve arm/hand function, fatigue, mood and quality of life. • We did not demonstrate improvement of cognitiv...

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Veröffentlicht in:	Clinical neurology and neurosurgery 2015-12, Vol.139, p.35-40
Hauptverfasser:	Pavsic, Katja, Pelicon, Katarina, Ledinek, Alenka Horvat, Sega, Sasa
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Aminopyridine 4-Aminopyridine - therapeutic use Activities of Daily Living Adult Affect Aged Arm/hand function Cognition Cognitive ability Cognitive function Depression Depression - psychology Exercise Test Fampridine Fatigue Female Humans Inventory Male Middle Aged Mood Multiple sclerosis Multiple Sclerosis, Chronic Progressive - drug therapy Multiple Sclerosis, Chronic Progressive - physiopathology Multiple Sclerosis, Chronic Progressive - psychology Multiple Sclerosis, Relapsing-Remitting - drug therapy Multiple Sclerosis, Relapsing-Remitting - physiopathology Multiple Sclerosis, Relapsing-Remitting - psychology Neurology Neurosurgery Patients Potassium Channel Blockers - therapeutic use Prospective Studies Quality of Life Questionnaires Studies Surveys and Questionnaires Walking
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Zusammenfassung:	Highlights • Fampridine is licensed to improve walking in all types of multiple sclerosis. • We examined fampridine's impact on various functions besides walking. • Fampridine seems to improve arm/hand function, fatigue, mood and quality of life. • We did not demonstrate improvement of cognitive function after fampridine treatment.
ISSN:	0303-8467 1872-6968
DOI:	10.1016/j.clineuro.2015.08.023