Inter-individual differences in pain processing investigated by functional magnetic resonance imaging of the brainstem and spinal cord

Inter-individual differences in pain processing investigated by functional magnetic resonance imaging of the brainstem and spinal cord

Highlights • The pain elicited by a heat stimulus varies widely across healthy participants. • fMRI of the brainstem/spinal cord show pain-related variations across individuals. • Structural equation modeling reveals connectivity that varies with pain ratings. • Individual differences in pain can ar...

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Veröffentlicht in:Neuroscience 2015-10, Vol.307, p.231-241
Hauptverfasser: Khan, H.S, Stroman, P.W
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
brain
Brain Stem - blood supply
brainstem
Female
fMRI
healthy
Healthy Volunteers
Humans
Image Processing, Computer-Assisted
Individuality
Magnetic Resonance Imaging
Male
Middle Aged
Neurology
Oxygen - blood
pain
Pain - etiology
Pain - pathology
Pain Measurement
Physical Stimulation - adverse effects
Psychophysics
spinal cord
Spinal Cord - blood supply
Young Adult
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Beschreibung
Zusammenfassung:Highlights • The pain elicited by a heat stimulus varies widely across healthy participants. • fMRI of the brainstem/spinal cord show pain-related variations across individuals. • Structural equation modeling reveals connectivity that varies with pain ratings. • Individual differences in pain can arise from modulation of spinal nociception.
ISSN:0306-4522
1873-7544
DOI:10.1016/j.neuroscience.2015.08.059