Improved lung function following dietary antioxidant supplementation in exercise-induced asthmatics

Highlights • Supplementation of Ascorbic acid (vitamin C) and α-tocopherol (vitamin E) leads to improvements in pulmonary function at minute 5 and minute 15 in forced vital capacity (FVC); forced expiratory volume in 1-s (FEV1 ); peak expiratory flow rate (PEFR); and forced expiratory flow between 2...

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Veröffentlicht in:Respiratory physiology & neurobiology 2016-01, Vol.220, p.95-101
Hauptverfasser: Kurti, Stephanie P, Murphy, Jill D, Ferguson, Christine S, Brown, Kelly R, Smith, Joshua R, Harms, Craig A
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Sprache:eng
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Zusammenfassung:Highlights • Supplementation of Ascorbic acid (vitamin C) and α-tocopherol (vitamin E) leads to improvements in pulmonary function at minute 5 and minute 15 in forced vital capacity (FVC); forced expiratory volume in 1-s (FEV1 ); peak expiratory flow rate (PEFR); and forced expiratory flow between 25 and 75% of vital capacity (FEF25–75% ) and minute 30 in FEV1 and FEF25–75% post-exercise following three week of supplementation in EIA subjects. • Supplementation also may improve FVC in subjects without EIA 5 and 15 min post-exercise. • Considering dietary antioxidant supplementation appears to help patients with EIA, this might help them become less dependent on medications and provide them alternative treatments for EIA.
ISSN:1569-9048
1878-1519
DOI:10.1016/j.resp.2015.09.012