Circulating levels of IGF-1, IGFBP-3, and IGF-1/IGFBP-3 molar ratio and colorectal adenomas: A meta-analysis

Highlights • IGF-1 was associated with increased risk of occurrence of advanced CRA. • IGF-1 was significantly associated with decreased risk of recurrence of CRA. • IGF-1/IGFBP-3 ratio was associated with decreased risk of recurrence of CRA.

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Bibliographische Detailangaben
Veröffentlicht in:	Cancer epidemiology 2015-12, Vol.39 (6), p.1026-1035
Hauptverfasser:	Yoon, Yeong Sook, Keum, NaNa, Zhang, Xuehong, Cho, Eunyoung, Giovannucci, Edward L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - epidemiology Adenoma - pathology Advanced adenoma Cancer Colorectal adenoma Colorectal cancer Colorectal Neoplasms - epidemiology Colorectal Neoplasms - pathology Epidemiology Hematology, Oncology and Palliative Medicine Humans Insulin Insulin-Like Growth Factor Binding Protein 3 - metabolism Insulin-like growth factor binding protein-3 Insulin-Like Growth Factor I - metabolism Insulin-like growth factor-1 Insulin-like growth factors Internal Medicine Meta-analysis Neoplasm recurrence Odds Ratio Risk Studies
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Beschreibung
Zusammenfassung:	Highlights • IGF-1 was associated with increased risk of occurrence of advanced CRA. • IGF-1 was significantly associated with decreased risk of recurrence of CRA. • IGF-1/IGFBP-3 ratio was associated with decreased risk of recurrence of CRA.
ISSN:	1877-7821 1877-783X
DOI:	10.1016/j.canep.2015.09.004