Frozen shoulder in HIV patients treated with indinavir : report of three cases

The development of HIV protease inhibitors has considerably improved the prognosis of infected patients. The treatment is, however, associated with adverse events that are unique to protease inhibitors. Indinavir thus shows a particular profile of adverse effects, with renal calculi or nail disorders, which do not appear with the other protease inhibitors. Recently, a few cases of frozen shoulder related to indinavir therapy have been reported in the literature. We describe three similar cases.