Drastically lowering the titer of waterborne bacteriophage PRD1 by exposure to immobilized hydrophobic polycations

Decrease in the titer of bacteriophage PRD1 (a model of animal adenoviruses) in aqueous solutions caused by the presence of systematically chemically derivatized surfaces was kinetically investigated. The greatest loss of infectivity--up to a 4-log reduction in the titer--was observed with immobiliz...

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Veröffentlicht in:Biotechnology letters 2004-11, Vol.26 (22), p.1695-1700
Hauptverfasser: GELMAN, Faina, LEWIS, Kim, KLIBANOV, Alexander M
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container_title Biotechnology letters
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creator GELMAN, Faina
LEWIS, Kim
KLIBANOV, Alexander M
description Decrease in the titer of bacteriophage PRD1 (a model of animal adenoviruses) in aqueous solutions caused by the presence of systematically chemically derivatized surfaces was kinetically investigated. The greatest loss of infectivity--up to a 4-log reduction in the titer--was observed with immobilized hydrophobic polyethylenimine-based and dendrimer-based polycations.
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source MEDLINE; SpringerLink Journals - AutoHoldings
subjects Adsorption
Aqueous solutions
Bacteriophage PRD1 - drug effects
Bacteriophage PRD1 - growth & development
Biological and medical sciences
Biotechnology
Cell Count
Cell Proliferation - drug effects
Cell Survival - drug effects
Fundamental and applied biological sciences. Psychology
Hydrophobic and Hydrophilic Interactions
Polyamines - pharmacology
Polyethyleneimine - pharmacology
Water Microbiology
Water Pollution - prevention & control
Water Purification - methods
title Drastically lowering the titer of waterborne bacteriophage PRD1 by exposure to immobilized hydrophobic polycations
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