Metastatic clear cell renal cell carcinoma: A review of current therapies and novel immunotherapies

Highlights • Treatment strategies for metastatic renal cell carcinoma have changed based on advances in basic science. • In the past 10–15 years the paradigm shifted from non-specific immunotherapy to targeted therapies. • There is currently a shift from targeted therapies to more specific immunothe...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Critical reviews in oncology/hematology 2015-12, Vol.96 (3), p.527-533
Hauptverfasser:	Thomas, Jacob S, Kabbinavar, Fairooz
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - therapeutic use Carcinoma Carcinoma, Renal Cell - immunology Carcinoma, Renal Cell - secondary Carcinoma, Renal Cell - therapy Combined Modality Therapy Dendritic cells Hematology, Oncology and Palliative Medicine Humans Immunotherapy Kidney Neoplasms - immunology Kidney Neoplasms - pathology Kidney Neoplasms - therapy Prognosis Programmed cell death 1 receptor Renal cell
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Treatment strategies for metastatic renal cell carcinoma have changed based on advances in basic science. • In the past 10–15 years the paradigm shifted from non-specific immunotherapy to targeted therapies. • There is currently a shift from targeted therapies to more specific immunotherapies. • The literature behind targeted therapies immunotherapies are reviewed.
ISSN:	1040-8428 1879-0461
DOI:	10.1016/j.critrevonc.2015.07.009