Impact of pneumococcal conjugate vaccines on childhood otitis media in the United Kingdom

Abstract Background Studies have demonstrated a reduction for otitis media (OM) following the introduction of seven-valent pneumococcal conjugate vaccine (PCV7), but this has not been evaluated in the United Kingdom (UK). Moreover, there are limited data on any additional impact of PCV13 introductio...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 2015-09, Vol.33 (39), p.5072-5079
Hauptverfasser:	Lau, Wallis C.Y, Murray, Macey, El-Turki, Aisha, Saxena, Sonia, Ladhani, Shamez, Long, Paul, Sharland, Mike, Wong, Ian C.K, Hsia, Yingfen
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Allergy and Immunology Antibiotics Child Child, Preschool Children Codes Computerized physician order entry Ear diseases Female General practitioners Heptavalent Pneumococcal Conjugate Vaccine - administration & dosage Heptavalent Pneumococcal Conjugate Vaccine - immunology Humans Immunization Incidence Infant Infant, Newborn Male Medical records Medical research Observational studies Otitis media Otitis Media - epidemiology Otitis Media - microbiology Pneumococcal conjugate vaccines Pneumococcal Infections - epidemiology Pneumococcal Infections - prevention & control Pneumococcal Vaccines - administration & dosage Pneumococcal Vaccines - immunology Pneumonia Prescriptions Primary care Retrospective Studies Streptococcus infections Streptococcus pneumoniae Studies Time series Trends United Kingdom - epidemiology Vaccines
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Abstract Background Studies have demonstrated a reduction for otitis media (OM) following the introduction of seven-valent pneumococcal conjugate vaccine (PCV7), but this has not been evaluated in the United Kingdom (UK). Moreover, there are limited data on any additional impact of PCV13 introduction in 2010. Methods We conducted an observational cohort study to investigate the trends in OM incidence and associated antibiotic prescriptions in children aged
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2015.08.022