Peter Brian Medawar and the discovery of acquired immunological tolerance

Highlights • Medawar and his co-workers showed that tolerance can be experimentally induced in fetal mice and in chick embryos. • Medawar was awarded the Nobel Prize in Physiology or Medicine with Burnet for their discovery of acquired immunologic tolerance. • In 1968, 15 years the seminal paper of...

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Veröffentlicht in:	Immunology letters 2015-10, Vol.167 (2), p.63-66
1. Verfasser:	Ribatti, Domenico
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Allergy and Immunology - history History of Medicine History, 20th Century Humans Immune Tolerance Innunology Medawar Nobel Prize Not-self Physiology - history Self Tolerance
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Highlights • Medawar and his co-workers showed that tolerance can be experimentally induced in fetal mice and in chick embryos. • Medawar was awarded the Nobel Prize in Physiology or Medicine with Burnet for their discovery of acquired immunologic tolerance. • In 1968, 15 years the seminal paper of Medawar, Good and FBach reported the first two successful human bone marrow transplants.
ISSN:	0165-2478 1879-0542
DOI:	10.1016/j.imlet.2015.07.004