Evolving trends in the dereplication of natural product extracts. 3: further lasiodiplodins from Lasiodiplodia theobromae, an endophyte from Mapania kurzii

Evolving trends in the dereplication of natural product extracts. 3: further lasiodiplodins from Lasiodiplodia theobromae, an endophyte from Mapania kurzii

Two further lasiodiplodins, (3R,4R)-4-hydroxy-de-O-methyl-lasiodiplodin and (E)-9-etheno-de-O-methyl-lasiodiplodin, together with three known lasiodiplodins from a cytotoxic extract obtained from a culture of Lasiodiplodia theobromae, an endophyte from the root tissues of Mapania kurzii (Cyperaceae)...

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Veröffentlicht in:Tetrahedron letters 2014-01, Vol.55 (2), p.453-455
Hauptverfasser: Sultan, Sadia, Sun, Lin, Blunt, John W., Cole, Anthony L.J., Munro, Murray H.G., Ramasamy, Kalavathy, Weber, Jean-Frédéric F.
Format: Artikel
Sprache:eng
Schlagworte:
Culture
Dereplication
Evolution
Lasiodiplodia theobromae
Lasiodiplodins
Microscale
Natural products
Rain forests
Roots
Tetrahedrons
Trends
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Beschreibung
Zusammenfassung:Two further lasiodiplodins, (3R,4R)-4-hydroxy-de-O-methyl-lasiodiplodin and (E)-9-etheno-de-O-methyl-lasiodiplodin, together with three known lasiodiplodins from a cytotoxic extract obtained from a culture of Lasiodiplodia theobromae, an endophyte from the root tissues of Mapania kurzii (Cyperaceae) from the Malaysian rain forest, were characterized on microgram scale.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2013.11.060