Monitoring Amyloid Sup35NM Growth with Label‐Free Electrical Detection Using a Field‐Effect Transistor Biosensor

Monitoring Amyloid Sup35NM Growth with Label‐Free Electrical Detection Using a Field‐Effect Transistor Biosensor

Semiconductor biosensing: An electrical assay based on the field‐effect transistor (FET) is developed for the detection of fibrous amyloid proteins without any labels. This assay distinguishes amyloid proteins possessing the cross‐β structure, and thereby monitors amyloid growth.

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Bibliographische Detailangaben
Veröffentlicht in:ChemElectroChem 2014-01, Vol.1 (1), p.51-54
Hauptverfasser: Hideshima, Sho, Wustoni, Shofarul, Kuroiwa, Shigeki, Nakanishi, Takuya, Koike‐Takeshita, Ayumi, Osaka, Tetsuya
Format: Artikel
Sprache:eng
Schlagworte:
amyloid growth
Assaying
biosensors
cross‐β structure
Field effect transistors
Labels
label‐free detection
Monitoring
Monitors
Proteins
Semiconductor devices
Semiconductors
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Beschreibung
Zusammenfassung:Semiconductor biosensing: An electrical assay based on the field‐effect transistor (FET) is developed for the detection of fibrous amyloid proteins without any labels. This assay distinguishes amyloid proteins possessing the cross‐β structure, and thereby monitors amyloid growth.
ISSN:2196-0216
2196-0216
DOI:10.1002/celc.201300151