A new multicomponent approach to highly functionalized 2,3-dihydroisoxazoles

A new multicomponent approach to highly functionalized 2,3-dihydroisoxazoles

The synthesis of highly functionalized 2,3-dihydroisoxazoles by a one-pot multicomponent reaction of an aldehyde, hydroxamic acid, and malononitrile or methyl cyanoacetate is described.

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Bibliographische Detailangaben
Veröffentlicht in:Tetrahedron letters 2014-01, Vol.55 (2), p.514-516
Hauptverfasser: Madabhushi, Sridhar, Godala, Kondal Reddy, Jillella, Raveendra, Mallu, Kishore Kumar Reddy, Chinthala, Narsaiah
Format: Artikel
Sprache:eng
Schlagworte:
2,3-Dihydroisoxazoles
Acetohydroxamic acid
Aldehyde
Aldehydes
Malononitrile
Methyl cyanoacetate
Multicomponent reaction
Synthesis
Tetrahedrons
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Beschreibung
Zusammenfassung:The synthesis of highly functionalized 2,3-dihydroisoxazoles by a one-pot multicomponent reaction of an aldehyde, hydroxamic acid, and malononitrile or methyl cyanoacetate is described.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2013.11.087