Synthetic studies toward biselides. Part 1: synthesis of the core carbon framework of biselides A, B, and E using Stille coupling

Biselides A and B are cytotoxic marine polyketides. We have achieved synthesis of the C-1–C-15 segment of biselides A and B by using Stille coupling and regioselective oxidative cleavage as key steps. Furthermore, we constructed the α,β-unsaturated lactone part of biselide E by using a similar strat...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Tetrahedron letters 2012-03, Vol.53 (11), p.1390-1392
Hauptverfasser:	Satoh, Yohsuke, Kawamura, Dai, Yamaura, Masashi, Ikeda, Yoichi, Ochiai, Yumi, Hayakawa, Ichiro, Kigoshi, Hideo
Format:	Artikel
Sprache:	eng
Schlagworte:	Biselides Carbon Cleavage Joining Lactones Polyketides Regioselective oxidative cleavage Segments Stille coupling Strategy Synthesis (chemistry) Tetrahedrons
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!