Copper-mediated trimethylsilyl azide in amination of bromoflavonoids to synthesize unique aminoflavonoids
Aminoflavonoids are unique antioxidants comparing to other abundant flavonoids in nature. Their syntheses and biological activities were scarcely reported. An effectively copper-mediated amination of the corresponding bromoflavonoids to synthesize a series of new aminoflavonoids is described. [Displ...
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Veröffentlicht in: | Tetrahedron 2014-06, Vol.70 (23), p.3657-3664 |
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container_title | Tetrahedron |
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creator | Shih, Tzenge-Lien Chou, Chi-En Liao, Wen-Yu Hsiao, Chih-Ang |
description | Aminoflavonoids are unique antioxidants comparing to other abundant flavonoids in nature. Their syntheses and biological activities were scarcely reported. An effectively copper-mediated amination of the corresponding bromoflavonoids to synthesize a series of new aminoflavonoids is described.
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doi_str_mv | 10.1016/j.tet.2014.04.022 |
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subjects | Aminoflavonoids Antioxidants Baker–Venkataraman rearrangement Biological Claisen–Schmidt reaction Copper-mediated amination Flavonoids Tetrahedrons Trimethylsilyl azide |
title | Copper-mediated trimethylsilyl azide in amination of bromoflavonoids to synthesize unique aminoflavonoids |
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