Copper-mediated trimethylsilyl azide in amination of bromoflavonoids to synthesize unique aminoflavonoids

Aminoflavonoids are unique antioxidants comparing to other abundant flavonoids in nature. Their syntheses and biological activities were scarcely reported. An effectively copper-mediated amination of the corresponding bromoflavonoids to synthesize a series of new aminoflavonoids is described. [Displ...

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Veröffentlicht in:Tetrahedron 2014-06, Vol.70 (23), p.3657-3664
Hauptverfasser: Shih, Tzenge-Lien, Chou, Chi-En, Liao, Wen-Yu, Hsiao, Chih-Ang
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container_end_page 3664
container_issue 23
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container_title Tetrahedron
container_volume 70
creator Shih, Tzenge-Lien
Chou, Chi-En
Liao, Wen-Yu
Hsiao, Chih-Ang
description Aminoflavonoids are unique antioxidants comparing to other abundant flavonoids in nature. Their syntheses and biological activities were scarcely reported. An effectively copper-mediated amination of the corresponding bromoflavonoids to synthesize a series of new aminoflavonoids is described. [Display omitted]
doi_str_mv 10.1016/j.tet.2014.04.022
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ispartof Tetrahedron, 2014-06, Vol.70 (23), p.3657-3664
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source ScienceDirect Journals (5 years ago - present)
subjects Aminoflavonoids
Antioxidants
Baker–Venkataraman rearrangement
Biological
Claisen–Schmidt reaction
Copper-mediated amination
Flavonoids
Tetrahedrons
Trimethylsilyl azide
title Copper-mediated trimethylsilyl azide in amination of bromoflavonoids to synthesize unique aminoflavonoids
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