Design and Fabrication of a Silicone Rubber-based Mediatorless Bioelectrode for Oxygen Reduction

In this work, a mediatorless bioelectrode has been constructed for the first time on a flexible silicone rubber sheet coated with homogeneous chitosan–carbon nanotubes composites. Bilirubin oxidase was employed as a model biocatalyst to reduce O2 to H2O. These novel fabricated electrodes showed good electrochemical properties and exhibited comparatively high operational stability even after 5 days of continuous operation. The results obtained here demonstrated the potential of silicone rubber-based materials as a promising platform for flexible bioelectronics in medical devices.