Novel betaines/mesoionic compounds via a simple and convenient MCR in aqueous micellar system: synthesis of thiazolo[2,3-a]isoquinolin-4-ium derivatives

Novel betaines/mesoionic compounds via a simple and convenient MCR in aqueous micellar system: synthesis of thiazolo[2,3-a]isoquinolin-4-ium derivatives

An inexpensive one-pot green methodology has been developed for the synthesis of thiazolo[2,3-a]isoquinolin-4-ium derivatives by the reaction of different derivatives of isoquinoline and 2-bromoacetophenone/bromoacetonitrile with benzoyl isothiocyanate in aqueous micellar medium.

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Veröffentlicht in:Tetrahedron letters 2014-05, Vol.55 (19), p.3059-3063
Hauptverfasser: Maity, Arindam, Chakraborty, Debanjana, Hazra, Abhijit, Bharitkar, Yogesh P., Kundu, Sandip, Maulik, Prakas R., Mondal, Nirup B.
Format: Artikel
Sprache:eng
Schlagworte:
1,3-Dipolar cycloaddition
Aqueous micellar system
Benzoyl isothiocyanate
Betaines
Derivatives
Mesoionic
Methodology
Multicomponent reaction
Synthesis (chemistry)
Tetrahedrons
Thiazolo[2,3-a]isoquinolin-4-ium
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Beschreibung
Zusammenfassung:An inexpensive one-pot green methodology has been developed for the synthesis of thiazolo[2,3-a]isoquinolin-4-ium derivatives by the reaction of different derivatives of isoquinoline and 2-bromoacetophenone/bromoacetonitrile with benzoyl isothiocyanate in aqueous micellar medium.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2014.03.122