A one-pot three-component reaction providing tricyclic 1,4-benzoxazepine derivatives

A one-pot three-component reaction providing tricyclic 1,4-benzoxazepine derivatives

A new one-pot, three-component reaction of aromatic aldehydes, 2-aminophenol, and dimedone for the synthesis of tricyclic 1,4-benzoxazepine derivatives in moderate to good yields is described.

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Veröffentlicht in:Tetrahedron letters 2013-06, Vol.54 (23), p.2983-2985
Hauptverfasser: Ghandi, Mehdi, Momeni, Tayebeh, Nazeri, Mohammad Taghi, Zarezadeh, Nahid, Kubicki, Maciej
Format: Artikel
Sprache:eng
Schlagworte:
1,4-Benzoxazepine
2-Aminophenol
Aldehydes
Derivatives
Dimedone
Enamines
Synthesis
Tetrahedrons
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Beschreibung
Zusammenfassung:A new one-pot, three-component reaction of aromatic aldehydes, 2-aminophenol, and dimedone for the synthesis of tricyclic 1,4-benzoxazepine derivatives in moderate to good yields is described.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2013.03.131