Voacalgines A–E, new indole alkaloids from Voacanga grandifolia
Five new indole alkaloids, voacalgines A–E (1–5) consisting of a C-mavacurine type of skeleton with 2,3-dihydroxybenzoate moiety, a macroline-type of skeleton, or a macroline-type of skeleton with C6 unit, were isolated from the bark of Voacanga grandifolia. Their relative structures were determined...
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| Veröffentlicht in: | Tetrahedron 2013-12, Vol.69 (51), p.10869-10875 |
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| container_end_page | 10875 |
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| container_issue | 51 |
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| container_title | Tetrahedron |
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| creator | Hirasawa, Yusuke Arai, Hiroko Rahman, Abdul Kusumawati, Idha Zaini, Noor Cholies Shirota, Osamu Morita, Hiroshi |
| description | Five new indole alkaloids, voacalgines A–E (1–5) consisting of a C-mavacurine type of skeleton with 2,3-dihydroxybenzoate moiety, a macroline-type of skeleton, or a macroline-type of skeleton with C6 unit, were isolated from the bark of Voacanga grandifolia. Their relative structures were determined by means of NMR data. Voacalgine A showed moderate cell growth inhibitory activities against HL-60 and HCT116 cells.
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| doi_str_mv | 10.1016/j.tet.2013.10.097 |
| format | Article |
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| ispartof | Tetrahedron, 2013-12, Vol.69 (51), p.10869-10875 |
| issn | 0040-4020 1464-5416 |
| language | eng |
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| source | Access via ScienceDirect (Elsevier) |
| subjects | Alkaloids Bark Cytotoxicity Indole alkaloid Indoles Nuclear magnetic resonance Tetrahedrons Voacalgine A Voacanga grandifolia |
| title | Voacalgines A–E, new indole alkaloids from Voacanga grandifolia |
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