Simple and convenient synthesis of fluoroalkenes via direct coupling of alcohols, alkynes and fluoroboric acid under metal-free conditions

A novel and convenient method for the synthesis of fluoroalkenes from simple starting materials has been developed under mild and metal-free conditions. A novel and convenient method for the synthesis of fluoroalkenes from alkynes, alcohols and fluoroboric acid has been developed under mild conditio...

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Veröffentlicht in:Tetrahedron letters 2014-07, Vol.55 (28), p.3750-3752
Hauptverfasser: Yan, Xiao-wei, Zhang, Qiang, Wei, Wei, Ji, Jian-xin
Format: Artikel
Sprache:eng
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Zusammenfassung:A novel and convenient method for the synthesis of fluoroalkenes from simple starting materials has been developed under mild and metal-free conditions. A novel and convenient method for the synthesis of fluoroalkenes from alkynes, alcohols and fluoroboric acid has been developed under mild conditions. The present protocol provides an attractive approach to access various fluoroalkenes from simple and commercially available starting materials without any metal catalyst, ligand or additive.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2014.05.069