Copper-catalyzed direct N-arylation of N-arylsulfonamides using diaryliodonium salts in water

Copper-catalyzed direct N-arylation of N-arylsulfonamides using diaryliodonium salts in water

An efficient copper-catalyzed N-arylation of N-arylsulfonamides with diaryliodonium salts is reported. The reaction employs diaryliodonium salts and N-arylsulfonamides in water at room temperature, giving the products in moderate to excellent yields.

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Veröffentlicht in:Tetrahedron letters 2014-07, Vol.55 (29), p.3856-3859
Hauptverfasser: Geng, Xu, Mao, Song, Chen, Liangshun, Yu, Jianjun, Han, Jianwei, Hua, Jianli, Wang, Limin
Format: Artikel
Sprache:eng
Schlagworte:
Arylation
Copper catalysis
C–N cross coupling
Diaryliodonium salts
Mild reaction conditions
Tetrahedrons
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Zusammenfassung:An efficient copper-catalyzed N-arylation of N-arylsulfonamides with diaryliodonium salts is reported. The reaction employs diaryliodonium salts and N-arylsulfonamides in water at room temperature, giving the products in moderate to excellent yields.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2014.05.082