Basic ionic liquid promoted heterocyclization to access fused imidazopyridines

A single step access to fused imidazopyridine involving [bmIm]OH promoted click cyclocondensation of N-methylisatin with 2-aminopyridine has been achieved. The title heterocyclic scaffolds were obtained in excellent yield with high purity. [bmIm]OH was found to be more attractive as it plays the rol...

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Veröffentlicht in:Tetrahedron letters 2013-09, Vol.54 (37), p.5083-5086
Hauptverfasser: Siddiqui, I.R., Shireen, Shamim, Shayna, Waseem, Malik Abdul, Abumhdi, Afaf A.H., Srivastava, Arjita, Srivastava, Anjali
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container_end_page 5086
container_issue 37
container_start_page 5083
container_title Tetrahedron letters
container_volume 54
creator Siddiqui, I.R.
Shireen
Shamim, Shayna
Waseem, Malik Abdul
Abumhdi, Afaf A.H.
Srivastava, Arjita
Srivastava, Anjali
description A single step access to fused imidazopyridine involving [bmIm]OH promoted click cyclocondensation of N-methylisatin with 2-aminopyridine has been achieved. The title heterocyclic scaffolds were obtained in excellent yield with high purity. [bmIm]OH was found to be more attractive as it plays the role of solvent, base, and catalyst.
doi_str_mv 10.1016/j.tetlet.2013.07.054
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source Elsevier ScienceDirect Journals Complete - AutoHoldings
subjects Catalysts
Heterocyclization
Imidazopyridine
Ionic liquid
Ionic liquids
Mild reaction conditions
Purity
Room temperature
Scaffolds
Solvents
Tetrahedrons
title Basic ionic liquid promoted heterocyclization to access fused imidazopyridines
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