Basic ionic liquid promoted heterocyclization to access fused imidazopyridines
A single step access to fused imidazopyridine involving [bmIm]OH promoted click cyclocondensation of N-methylisatin with 2-aminopyridine has been achieved. The title heterocyclic scaffolds were obtained in excellent yield with high purity. [bmIm]OH was found to be more attractive as it plays the rol...
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Veröffentlicht in: | Tetrahedron letters 2013-09, Vol.54 (37), p.5083-5086 |
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creator | Siddiqui, I.R. Shireen Shamim, Shayna Waseem, Malik Abdul Abumhdi, Afaf A.H. Srivastava, Arjita Srivastava, Anjali |
description | A single step access to fused imidazopyridine involving [bmIm]OH promoted click cyclocondensation of N-methylisatin with 2-aminopyridine has been achieved. The title heterocyclic scaffolds were obtained in excellent yield with high purity. [bmIm]OH was found to be more attractive as it plays the role of solvent, base, and catalyst. |
doi_str_mv | 10.1016/j.tetlet.2013.07.054 |
format | Article |
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subjects | Catalysts Heterocyclization Imidazopyridine Ionic liquid Ionic liquids Mild reaction conditions Purity Room temperature Scaffolds Solvents Tetrahedrons |
title | Basic ionic liquid promoted heterocyclization to access fused imidazopyridines |
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